Incella’s technology


Incella’s technology: our thiol-yne based combinatorial click chemistry method allows parallel, high-throughput synthesis of hundreds of novel lipid-like chemicals in a cost effective manner. Every lipid-like molecule can be used to produce a novel transfection reagent with different properties. We combine our expertise in chemistry and biology to create an interdisciplinary research and development environment that encompasses chemical design, synthesis, liposomal reagent preparation, cell-based screening assays as well as identification and final optimization of novel transfection reagents.

Pavel Levkin receives Heinz Maier-Leibnitz Prize


Chemist Dr. Pavel Levkin from the Karlsruhe Institute of Technology (KIT) received the 2015 Heinz Maier-Leibnitz Prize. This award, issued by the German Research Foundation (DFG), is the most important prize for young researchers in Germany. Research in cell/surface interaction, developing biofunctional materials and extremely hydrophobic surfaces along with nanoparticles for targeted medication and gene transport are among Pavel Levkin’s scientific focal points. He achieved great scientific success with the synthesis of lipid-like molecules to modify the genes of cells.

Prostaglandin E2 Receptor Indispensable for Ovulation


Hagiwara, Akane, et al. "Luteinizing Hormone-Induced Expression of Ptger4b, a Prostaglandin E2 Receptor Indispensable for Ovulation of the Medaka Oryzias latipes, Is Regulated by a Genomic Mechanism Involving Nuclear Progestin Receptor."

New Generation of Transfection Reagents


Jochen Kratsch on a presentation at a meeting in Paris about Novel Transfection Reagents using Combinatorial Chemistry and High-Throughput Cell Screening.

The LIM Domain Protein nTRIP6 Recruits the Mediator Complex to AP-1-Regulated Promoters


Diefenbacher ME, Reich D, Dahley O, Kemler D, Litfin M, et al. "The LIM Domain Protein nTRIP6 Recruits the Mediator Complex to AP-1-Regulated Promoters."

ScreenFect®A for mRNA analysis


Latest publication using ScreenFect®A for mRNA analysis